Alessandro Paiardini Selected Research

Transaminases (Aminotransferases)

1/2019	R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features.
8/2013	Crystal structure of the S187F variant of human liver alanine: glyoxylate [corrected] aminotransferase associated with primary hyperoxaluria type I and its functional implications.

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Alessandro Paiardini Research Topics

Disease

20	Neoplasms (Cancer) 02/2024 - 09/2010
4	Primary Hyperoxaluria (Oxaluria, Primary) 08/2013 - 11/2007
3	Pyridoxamine 5-Prime-Phosphate Oxidase Deficiency 12/2018 - 01/2017
3	Lung Neoplasms (Lung Cancer) 01/2018 - 01/2016
3	Parkinson Disease (Parkinson's Disease) 01/2017 - 12/2011
3	Malaria 01/2015 - 06/2013
2	Persistent Infection 12/2023 - 08/2023
2	Bacillary Dysentery (Shigellosis) 01/2023 - 01/2023
2	Septic Shock (Toxic Shock Syndrome) 01/2023 - 01/2022
2	Infections 04/2022 - 11/2014
2	Brain Diseases (Brain Disorder) 12/2017 - 01/2017
2	Primary hyperoxaluria type 1 01/2012 - 03/2009
1	Inflammation (Inflammations) 01/2024
1	Foodborne Diseases 01/2024
1	Wounds and Injuries (Trauma) 01/2024
1	Carcinogenesis 01/2023
1	Breast Neoplasms (Breast Cancer) 01/2023
1	Sepsis (Septicemia) 01/2023
1	Metrorrhagia (Spotting) 01/2022
1	Choroideremia 01/2022
1	Neuroblastoma 12/2021
1	Starvation 11/2020
1	Neoplasm Metastasis (Metastasis) 11/2020
1	Adenocarcinoma of Lung 11/2020
1	Colorectal Neoplasms (Colorectal Cancer) 05/2020
1	Melanoma (Melanoma, Malignant) 05/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2019
1	Gyrate Atrophy 01/2019
1	Hypercalciuria 01/2018
1	Hypocalcemia 01/2018
1	Nephrocalcinosis 01/2018
1	Tourette Syndrome (Tourette's Syndrome) 01/2017

Drug/Important Bio-Agent (IBA)

7	EnzymesIBA 11/2016 - 11/2007
5	Phosphotransferases (Kinase)IBA 03/2023 - 05/2017
5	Serine (L-Serine)FDA Link 11/2020 - 05/2013
5	Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)IBA 11/2020 - 05/2013
4	Protein Isoforms (Isoforms)IBA 01/2023 - 01/2016
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2010
4	Glycine (Aminoacetic Acid)FDA LinkGeneric 11/2020 - 02/2010
4	CarbonIBA 01/2018 - 05/2013
4	PyridoxalIBA 08/2013 - 11/2006
4	Alanine-glyoxylate transaminase (alanine-glyoxylate aminotransferase)IBA 08/2013 - 11/2007
3	Anti-Bacterial Agents (Antibiotics)IBA 12/2023 - 04/2022
3	AminopeptidasesIBA 01/2015 - 06/2013
2	SuperantigensIBA 01/2023 - 01/2022
2	Aurora Kinase AIBA 01/2023 - 12/2021
2	Peptides (Polypeptides)IBA 01/2022 - 04/2013
2	Amino Acids FDA Link 11/2020 - 05/2013
2	artemisinin (artemisinine)IBA 05/2020 - 11/2014
2	Transaminases (Aminotransferases)IBA 01/2019 - 08/2013
2	RNA (Ribonucleic Acid)IBA 01/2019 - 01/2019
2	Pyridoxine (Pyridoxin)FDA LinkGeneric 12/2017 - 01/2017
2	purineIBA 11/2016 - 05/2013
2	Antimalarials (Antimalarial Agents)IBA 01/2015 - 11/2014
2	glyoxylic acid (glyoxylate)IBA 08/2013 - 01/2012
2	Dopa DecarboxylaseIBA 01/2012 - 12/2011
2	Dopamine (Intropin)FDA LinkGeneric 01/2012 - 12/2011
2	Serotonin (5 Hydroxytryptamine)IBA 01/2012 - 12/2011
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 02/2024
1	Enterotoxins (Enterotoxin)IBA 01/2024
1	Oxygen (Dioxygen)IBA 12/2023
1	Arginine (L-Arginine)FDA Link 08/2023
1	viral interferon regulatory factorsIBA 01/2023
1	LigandsIBA 01/2023
1	CytokinesIBA 01/2023
1	Staphylococcal enterotoxin AIBA 01/2023
1	Interferon-alpha (Interferon Alfa)IBA 01/2023
1	VaccinesIBA 01/2023
1	Histone DemethylasesIBA 01/2023
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022
1	Retinaldehyde (Retinal)IBA 01/2022
1	Peptide LibraryIBA 01/2022
1	Aurora KinasesIBA 12/2021
1	PHA 680626IBA 12/2021
1	Transcription Factors (Transcription Factor)IBA 12/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2020
1	Adenosine Monophosphate (AMP)IBA 11/2020
1	Adenosine Triphosphate (ATP)IBA 11/2020
1	Adenylate KinaseIBA 11/2020
1	QuinazolinonesIBA 05/2020
1	CateninsIBA 05/2020
1	Paclitaxel (Taxol)FDA LinkGeneric 05/2020
1	artesunic acidIBA 05/2020
1	CamptothecinIBA 05/2020
1	TankyrasesIBA 05/2020
1	N-methyladenosineIBA 01/2019
1	OrnithineIBA 01/2019
1	Ornithine-Oxo-Acid Transaminase (Ornithine Aminotransferase)IBA 01/2019
1	5-fluoromethylornithineIBA 01/2019
1	SaltsIBA 01/2019
1	Adenosine (Adenocard)FDA LinkGeneric 01/2019
1	6-methyladenineIBA 01/2019
1	Pyridoxaminephosphate OxidaseIBA 12/2018
1	Thymidine Monophosphate (TMP)IBA 01/2018
1	MagnesiumIBA 01/2018
1	claudin 16IBA 01/2018
1	Leucine (L-Leucine)FDA Link 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 01/2017

Therapy/Procedure

2	Therapeutics 01/2021 - 11/2014
1	Ligation 01/2022